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Strains and CFU

Probiotic strains explained in plain English

The names on a probiotic label can look daunting, yet they tell you exactly which microbes are in the pack. This guide explains probiotic strains, from the difference between lactobacilli and bifidobacteria to strain codes and the 2020 name changes, so you can compare labels with confidence.

  • Current and former species names
  • What strain codes tell you
  • Yeasts, spore-formers and prebiotics
Scientist in gloves adjusting a laboratory microscope
Know your strains

Species table

Common probiotic strains explained, with their current names

Many Lactobacillus species were renamed in 2020, so labels may show either the new or the old name. The table gives current names with former names in brackets. It describes where each species usually appears, not what it does.

SpeciesGroupTypically found inNotes
Lactobacillus acidophilusLactobacilliCapsules, powdersKept its name in 2020 and appears in many multi-strain blends
Lacticaseibacillus rhamnosus (formerly L. rhamnosus)LactobacilliCapsules, powders, dropsMany different strains are sold under this species
Lacticaseibacillus paracasei (formerly L. paracasei)LactobacilliCapsules, powdersCommon in multi-strain products
Lactiplantibacillus plantarum (formerly L. plantarum)LactobacilliCapsules, powders, sachetsComparatively tolerant of processing
Limosilactobacillus reuteri (formerly L. reuteri)LactobacilliDrops, chewablesOften supplied in oil-based drops
Lactobacillus gasseri and L. crispatusLactobacilliCapsulesBoth kept the Lactobacillus name in 2020
Bifidobacterium longum, B. breve, B. bifidumBifidobacteriaCapsules, powders, dropsSensitive to oxygen, so packaging matters
Bifidobacterium animalis subsp. lactisBifidobacteriaCapsules, powders, chewablesOften shortened to B. lactis on labels
Streptococcus thermophilusLactic acid bacteriaPowders, capsulesAlso one of the cultures used to make yoghurt
Saccharomyces boulardiiProbiotic yeastCapsules, sachetsA yeast rather than a bacterium, usually listed separately
Bacillus coagulans (now Heyndrickxia coagulans)Spore-formersGummies, chewables, capsulesSpores tolerate heat
Bacillus subtilisSpore-formersCapsules, gummiesForms hardy spores

The basics

Lactobacillus vs Bifidobacterium: how the two groups differ

Lactobacilli and bifidobacteria are the two groups you will see most often on probiotic labels. Lactobacilli are lactic acid bacteria, familiar from fermented foods such as yoghurt and sauerkraut, and many of them cope reasonably well with processing. Bifidobacteria are more sensitive to oxygen, so products that contain them tend to rely on protective packaging such as foil blisters or sealed sachets.

Neither group is better than the other. Research is specific to individual strains, so a finding about one strain does not automatically apply to another strain of the same species, let alone to a whole group. Many products combine species from both groups, and the label should list each one.

What strain codes tell you

A full strain name has a genus, a species and a strain code. The genus and species tell you what kind of microbe it is, and the code, a short run of letters or numbers, identifies one particular strain within that species. A label that lists only species names makes it hard to compare products or to look up what has been published about the strains inside.

Why many names changed in 2020

In 2020 the old Lactobacillus genus was split into several new groups after genetic analysis showed it held very different bacteria. Lactobacillus rhamnosus became Lacticaseibacillus rhamnosus, for example, and Lactobacillus plantarum became Lactiplantibacillus plantarum. The microbes themselves did not change, so a product using the old name is not out of date, and some labels print both.

Beyond lactobacilli

Saccharomyces boulardii and spore-forming probiotics

Saccharomyces boulardii, a probiotic yeast

S. boulardii is a yeast rather than a bacterium, and labels sometimes call it Saccharomyces cerevisiae var. boulardii. It is usually sold in capsules or sachets and is often listed separately from bacterial cultures, sometimes with its own count. Our guide on how to read a probiotic label shows where to find it.

Spore-forming Bacillus species

Species such as Bacillus coagulans and Bacillus subtilis form spores, a dormant state with a tough outer coat. Spores tolerate heat far better than most cultures, which is why they suit probiotic gummies and chewables.

Synbiotics and added ingredients

Prebiotics, postbiotics and added vitamins

Some products pair live cultures with a prebiotic fibre, and these are often called synbiotics. Others add heat-treated cultures or vitamins and minerals. Each of these appears in the ingredients list, so it helps to know what they are.

  • Prebiotic fibres: inulin, fructo-oligosaccharides (FOS) and galacto-oligosaccharides (GOS), which are fibres that bacteria can use rather than live microbes. Some people find they cause wind.
  • Postbiotics: cultures that have been heat-treated so they are no longer alive, sometimes listed as heat-killed or inactivated. They are not part of a CFU count.
  • Vitamins and minerals: nutrients such as vitamin D or zinc, which can carry authorised claims when present in a significant amount.

Powders tend to carry the most fibre, as our page on probiotic powders and sachets explains.

How added ingredients affect claims

No health claims are currently authorised for probiotics in Great Britain. When a pack says "vitamin D contributes to the normal function of the immune system", the claim belongs to the vitamin, not to the cultures.

Our probiotic quality checklist covers other wording to watch for.

Comparing products

Using strain names when you compare probiotics

When you compare two products, line up the full strain names first, then check the CFU and the date it applies to. Products that share a species may contain quite different strains, so matching the codes is the only way to tell whether two labels describe the same culture. The guide on how to choose a probiotic supplement puts these checks in order.

Format matters too, because not every strain survives every format. Most lactobacilli and bifidobacteria are found in probiotic capsules, powders and drops, while gummies mostly rely on spore-formers. If a name on a label is unfamiliar, ask us a question and Probiotic Supplements UK will explain it.

FAQs

Probiotic strain questions

Is Lactobacillus better than Bifidobacterium?

Neither group is better in general. Research is specific to individual strains, so the full strain name tells you more than the group it belongs to. Many products combine species from both.

Why does my label use a different name from the one I searched for?

Many Lactobacillus species were renamed in 2020, so you may see Lacticaseibacillus rhamnosus where you expected Lactobacillus rhamnosus. The microbe is the same, and some labels print both names to help shoppers.

Are more strains better than fewer?

Not automatically. A product with a few clearly named strains and a count stated until the best-before date can tell you more than a long list with no strain codes. Follow the label for how much to take.

Are probiotic cultures suitable for vegans?

Many are, but not all, because some cultures are grown on dairy-based media. Look for a vegan or vegetarian statement on the pack, and check the capsule shell too, as some are made from gelatine.

Ask us about an unfamiliar strain name

Send us the strain names from a label and we will explain what each part means and whether it was renamed. We answer by email and do not recommend brands.